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The Effect of Protectants and pH Changes on the Cellular Growth and Succinic Acid Yield of Mannheimia succiniciproducens LPK7
- Oh, Young Hoon;
- Oh, In Jae;
- Jung, Changkyou;
- Lee, Sang Yup;
- Lee, Jinwon
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7초록
The harmful effects of succinic acid and oxidative stress on cell growth were determined during batch fermentation with Mannheimia succiniciproducens LPK7, a powerful succinic acid-producing strain, and conditions were optimized to minimize these effects. In terms of toxicity, the cell concentration decreased as the concentration of succinic acid increased. By changing the pH from 6.5 to 7 during fermentation, the cell concentration increased by about 10%, and the level of succinic acid production was 6% higher than that of the control. In addition, by introducing protectants, the cell concentration increased by about 10%, and the level of succinic acid produced was increased by 3%.
키워드
Mannheimia succiniciproducens LPK7; succinic acid; protectants (biotin, glutathione, trehalose); cellular growth; oxidative stress; ACTINOBACILLUS-SUCCINOGENES; ANAEROBIOSPIRILLUM-SUCCINICIPRODUCENS; PHOSPHOENOLPYRUVATE CARBOXYKINASE; FERMENTATION; BACTERIUM
- 제목
- The Effect of Protectants and pH Changes on the Cellular Growth and Succinic Acid Yield of Mannheimia succiniciproducens LPK7
- 저자
- Oh, Young Hoon; Oh, In Jae; Jung, Changkyou; Lee, Sang Yup; Lee, Jinwon
- 발행일
- 2010-12
- 유형
- Article
- 권
- 20
- 호
- 12
- 페이지
- 1677 ~ 1680