Colorimetric tracking of protein structural evolution based on the distance-dependent light scattering of embedded gold nanoparticles

Choi, Inhee; Yang, Young In; Jeong, Eunhye; Kim, Kihoon; Hong, Surin; Kang, Taewook; Yi, Jongheop

doi:10.1039/c2cc17174k

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Colorimetric tracking of protein structural evolution based on the distance-dependent light scattering of embedded gold nanoparticles

Choi, Inhee;
Yang, Young In;
Jeong, Eunhye;
Kim, Kihoon;
Hong, Surin;
... Kang, Taewook;
외 1명

Citations

WEB OF SCIENCE

16

Citations

SCOPUS

17

초록

In this communication, we describe a new, simplified colorimetric method for in situ tracking of structural evolution of Cu/Zn-superoxide dismutase (SOD1) aggregates, based on changes in plasmonic coupling between gold nanoparticles (GNPs) embedded along the structural backbone of the SOD1 aggregates.

키워드

AMYOTROPHIC-LATERAL-SCLEROSIS; CU/ZN SUPEROXIDE-DISMUTASE; SINGLE GOLD; METAL-IONS; AGGREGATION; SOD1; MECHANISM; MUTANTS; FORM

제목: Colorimetric tracking of protein structural evolution based on the distance-dependent light scattering of embedded gold nanoparticles

저자: Choi, Inhee; Yang, Young In; Jeong, Eunhye; Kim, Kihoon; Hong, Surin; Kang, Taewook; Yi, Jongheop

DOI: 10.1039/c2cc17174k

발행일: 2012

유형: Article

저널명: Chemical Communications

권: 48

호: 17

페이지: 2286 ~ 2288