Stereoselective synthesis of enantiomerically pure D-threo-PDMP;: manipulation of a core 2,3-diamino alcohol unit

Shin, SH; Han, EY; Park, CS; Lee, WK; Ha, HJ

doi:10.1016/S0957-4166(00)00319-0

상세 보기

Stereoselective synthesis of enantiomerically pure D-threo-PDMP;: manipulation of a core 2,3-diamino alcohol unit

Shin, SH;
Han, EY;
Park, CS;
Lee, WK;
Ha, HJ

Citations

WEB OF SCIENCE

30

Citations

SCOPUS

28

초록

The C(3)-N bond of various non-activated enantiomerically pure aziridine-2-methanols was regioselectively cleaved by nitrogen nucleophiles to provide a variety of beta-aminoalanine derivatives in high yields. (C) 2000 Published by Elsevier Science Ltd.

키워드

RING-OPENING REACTIONS; AMINO-ACIDS; ASYMMETRIC-SYNTHESIS; VICINAL DIAMINES; AZIRIDINES; PSEUDOSUGARS; CARCINOMA; INHIBITOR; MECHANISM; CLEAVAGE

제목: Stereoselective synthesis of enantiomerically pure D-threo-PDMP;: manipulation of a core 2,3-diamino alcohol unit

저자: Shin, SH; Han, EY; Park, CS; Lee, WK; Ha, HJ

DOI: 10.1016/S0957-4166(00)00319-0

발행일: 2000-08-25

유형: Article

저널명: Tetrahedron Asymmetry

권: 11

호: 16

페이지: 3293 ~ 3301