One-pot solvent-free reductive amination with a solid ammonium carbamate salt from CO2 and amine

  • Kang, Philjun
  • Lee, Kyu Myung
  • Lee, Won Koo
  • Lee, Kyu Hyung
  • Lee, Byeongno
  • 외 2명
Citations

WEB OF SCIENCE

8
Citations

SCOPUS

9

초록

Many amines are liquid and their handling is inconvenient compared with the corresponding solids. We transformed a liquid (S)-(-)-1-phenylethylamine 1 to the corresponding neutral solid form 2 by reacting with carbon dioxide. We performed reductive amination of 2 with various aldehydes 3 under solvent-free conditions to provide secondary amines 5 in high yields.

키워드

CARBON-DIOXIDEPALLADIUMALDEHYDESESTERHYDROGENATIONKETONESACIDDERIVATIVESHYDRAZINECHLORIDE
제목
One-pot solvent-free reductive amination with a solid ammonium carbamate salt from CO2 and amine
저자
Kang, PhiljunLee, Kyu MyungLee, Won KooLee, Kyu HyungLee, ByeongnoCho, JaeheungHur, Nam Hwi
DOI
10.1039/c4ra07558g
발행일
2014
유형
Article
저널명
RSC Advances
4
86
페이지
46203 ~ 46207