Electrochemical immunosensor for prostate-specific antigen using self-assembled oligophenylethynylenethiol monolayer containing dendrimer

  • Namgung, Mi-Ok
  • Jung, Seul-Ki
  • Chung, Chan Moon
  • Oh, Se-Young
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초록

Electrochemical immunosensor for prostate-specific antigen. (PSA) was fabricated with a self-assembled 4-(2-(4-(acetylthio)phenyl)ethynyl)benzoic acid (APBA) as a bioreceptor. In order to enhance the electrochemical activity of PSA detection, poly(amidoamine) dendrimer was linked on the APBA self-assembled monolayer (SAM). The formation and electrical properties of the SAMs were investigated by surface plasmon resonance and cyclic voltammetry, respectively. The surface morphology of PSA sandwich complex onto the APBA SAM was studied by atomic force microscopy. (c) 2009 Elsevier B.V. All rights reserved.

키워드

Self-assembled oligophenylethynylenethiol monolayerElectrochemical immunosensorProstate-specific antigenSurface plasmon resonanceElectrochemical activityIMMUNOASSAYFABRICATION
제목
Electrochemical immunosensor for prostate-specific antigen using self-assembled oligophenylethynylenethiol monolayer containing dendrimer
저자
Namgung, Mi-OkJung, Seul-KiChung, Chan MoonOh, Se-Young
DOI
10.1016/j.ultramic.2009.03.039
발행일
2009-07
유형
Article; Proceedings Paper
저널명
Ultramicroscopy
109
8
페이지
907 ~ 910