Highly diastereoselective reduction of enantiomerically pure aziridino ketones

초록

Various enantiomerically pure aziridino ketones were prepared from the corresponding secondary alcohols by Swern oxidation. Those configurationally stable alpha-amino ketones were stereoselectively reduced by L-Selectride(R) to provide the corresponding alcohol with high diastereoselectivities and chemical yields. Copyright (C) 1996 Elsevier Science Ltd

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