Influenza A (H1N1) virus detection using QDoT-aptamer beacon in emission light guidance based 3D photonic crystal

초록

This paper proposed quantum dot (Qdot)-aptamer beacon based biosensor for highly sensitive influenza A (H1N1) virus detection using emission light guidance by 3D photonic crystal (PC). The proposed biosensor with 3D nanoporous structure was fabricated in simple and cost-effective way. In addition, output signal can be enhanced through emission light guidance, and wavelength of guided emission light can be engineered by changing nanopore size. Due to high signal-to-noise ratio, fluorescent signal was easily detected, and ultra-low limit of detection (LOD) of 138 pg/ml was obtained. Due to the enhance emission signal, the target virus can be easily detected with only a low-cost and portable setup and a commercial smartphone. © 17CBMS-0001.

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