Total synthesis, structural revision, and absolute configuration of (+)-clavosolide A

  • Son, JB
  • Kim, SN
  • Kim, NY
  • Lee, DH
Citations

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초록

Enantioselective synthesis of 3, a revised structure for clavosolide A, was completed. Both H-1 and C-13 NMR spectra of the natural and synthetic compounds were identical, and optical rotation measurements identified the absolute configuration of the natural clavosolide A as the enantiomer of 3.

키워드

1,5-ASYMMETRIC INDUCTIONSELECTIVE REDUCTIONSALKYL-HALIDESASSIGNMENTGLYCOSIDESFRAGMENTHYDRIDE
제목
Total synthesis, structural revision, and absolute configuration of (+)-clavosolide A
저자
Son, JBKim, SNKim, NYLee, DH
DOI
10.1021/ol052851n
발행일
2006-02-16
유형
Article
저널명
Organic Letters
8
4
페이지
661 ~ 664