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An efficient synthesis of morpholin-2-one derivatives using glycolaldehyde dimer by the Ugi multicomponent reaction
- Kim, YB;
- Choi, EH;
- Keum, G;
- Kang, SB;
- Lee, DH;
- 외 2명
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81초록
[GRAPHICS] A new one-pot procedure for the efficient synthesis of novel 3-substituted morpholin-2-one-5-carboxamide derivatives using commercially available glycolaldehyde dimer as a bifunctional component with various alpha -amino acids and isocyanides by the Ugi five-center three-component reaction (U-5C-3CR) was developed.
키워드
SOLUTION-PHASE SYNTHESIS; ARMSTRONGS CONVERTIBLE ISONITRILE; ALPHA-AMINO-ACIDS; 4-COMPONENT CONDENSATION; LIBRARIES; ISOCYANIDES; PYRROLES; ALCOHOLS; LACTAMS; RESIN
- 제목
- An efficient synthesis of morpholin-2-one derivatives using glycolaldehyde dimer by the Ugi multicomponent reaction
- 저자
- Kim, YB; Choi, EH; Keum, G; Kang, SB; Lee, DH; Koh, HY; Kim, YS
- 발행일
- 2001-12-27
- 유형
- Article
- 저널명
- Organic Letters
- 권
- 3
- 호
- 26
- 페이지
- 4149 ~ 4152