An efficient synthesis of α-amino-δ-valerolactones by the Ugi five-center three-component reaction

Kim, Young Bae; Park, Soo Jung; Keum, Gyo Chang; Jang, Min Seok; Kang, Soon Bang; Lee, Duck Hyung; Kim, You Seung

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An efficient synthesis of α-amino-δ-valerolactones by the Ugi five-center three-component reaction

Kim, Young Bae;
Park, Soo Jung;
Keum, Gyo Chang;
Jang, Min Seok;
Kang, Soon Bang;
... Lee, Duck Hyung;
외 1명

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12

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13

초록

A novel approach to alpha-amino-delta-valerolactone derivatives 8 by the intramolecular Ugi five-center three-component reaction (U-5C-3CR) using the multifunctional starting material, L-pentahomoserine 5 is described.

키워드

multicomponent reactions; combinatorial chemistry; Ugi reaction; L-pentahomoserine; glycolaldehyde dimer; SOLUTION-PHASE SYNTHESIS; ARMSTRONGS CONVERTIBLE ISONITRILE; 4-COMPONENT CONDENSATION; MULTICOMPONENT REACTIONS; SOLID SUPPORT; LIBRARIES; ACIDS; ISOCYANIDES; PYRROLES; LACTAMS

제목: An efficient synthesis of α-amino-δ-valerolactones by the Ugi five-center three-component reaction

저자: Kim, Young Bae; Park, Soo Jung; Keum, Gyo Chang; Jang, Min Seok; Kang, Soon Bang; Lee, Duck Hyung; Kim, You Seung

발행일: 2002-09

유형: Article

저널명: Bulletin of the Korean Chemical Society

권: 23

호: 9

페이지: 1277 ~ 1284