Preparation of 2,3-diaminopropionate from ring opening of aziridine-2-carboxylate

Kim, Y; Ha, HJ; Han, KS; Ko, SW; Yun, HS; Yoon, HJ; Kim, MS; Lee, WK

doi:10.1016/j.tetlet.2005.04.039

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Preparation of 2,3-diaminopropionate from ring opening of aziridine-2-carboxylate

Kim, Y;
Ha, HJ;
Han, KS;
Ko, SW;
Yun, HS;
... Lee, WK;
외 2명

Citations

WEB OF SCIENCE

41

Citations

SCOPUS

43

초록

Ring opening reaction of an enantiomerically pure aziridine-2-carboxylate with an azide nucleophile under aqueous acidic media proceeded efficiently and stereoselectively to give 3-amino-2-azidopropionate which is converted to orthogonally protected 2.3-diaminopropionate. (c) 2005 Elsevier Ltd. All rights reserved.

키워드

AMINO-ACIDS; CERIUM(III) CHLORIDE; EFFICIENT SYNTHESIS; PROTECTING GROUPS; SIDE-CHAIN; AZIRIDINES; DERIVATIVES; INHIBITORS; COMPLEXES; EPOXIDES

제목: Preparation of 2,3-diaminopropionate from ring opening of aziridine-2-carboxylate

저자: Kim, Y; Ha, HJ; Han, KS; Ko, SW; Yun, HS; Yoon, HJ; Kim, MS; Lee, WK

DOI: 10.1016/j.tetlet.2005.04.039

발행일: 2005-06-20

유형: Article

저널명: Tetrahedron Letters

권: 46

호: 25

페이지: 4407 ~ 4409