Integrated 64-Channel Spatiotemporally Patterned Multipolar Neural Stimulator with 150nA-10 mA Current Range at 8V-20V Voltage Compliance

초록

This work presents a 64-channel current-mode neural stimulator with 96 dB current dynamic range from 150 nA to 10 mA and voltage compliance ranging from 8 V to 20 V. Each channel supports dynamically configurable arbitrary spatiotemporal stimulation profiles through a 10-b DAC temporal envelope at 125 ksps and a 6-b spatial per-channel multiplying gain over a programmable SPI. Fabricated in 180 nm HV BCD technology, the stimulator demonstrates <2% variation across the current range under dynamic supply voltage scaling from ± 5.5 V to ± 12 V and <5 mV residual voltage through active shunt charge balancing for monopolar, bipolar, and multipolar stimulation modes. Benchtop and ex-vivo tests demonstrate multipolar stimulation and flexible interfacing with both microand macroelectrodes, validating compatibility with microscale experimental setups and high-current clinical stimulation protocols. © 2025 IEEE.

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