N-Methylative aziridine ring opening: asymmetric synthesis of hygroline, pseudohygroline, and hygrine

Lee, Jaedeok; Lee, Jae Eun; Ha, Hyun-Joon; Son, Se In; Lee, Won Koo

doi:10.1016/j.tetlet.2014.12.133

상세 보기

N-Methylative aziridine ring opening: asymmetric synthesis of hygroline, pseudohygroline, and hygrine

Lee, Jaedeok;
Lee, Jae Eun;
Ha, Hyun-Joon;
Son, Se In;
Lee, Won Koo

Citations

WEB OF SCIENCE

17

Citations

SCOPUS

16

초록

Asymmetric syntheses of biologically and pharmaceutically important (-)-hygroline, (-)-pseudohygroline, and (-)-hygrine were achieved by a newly developed 'N-methylative aziridine ring opening reactions' of (2S)-methoxycarbonylethylaziridine as a key step. (C) 2014 Elsevier Ltd. All rights reserved.

키워드

Aziridine; Ring opening; Hygroline; Pseudohygroline; Hygrine; TROPANE ALKALOIDS; ENANTIOSELECTIVE SYNTHESIS; EFFICIENT SYNTHESIS; ANODIC-OXIDATION; FORMAL SYNTHESIS; PYRROLIDINE; PIPERIDINE; REDUCTION; CHEMISTRY; KETONES

제목: N-Methylative aziridine ring opening: asymmetric synthesis of hygroline, pseudohygroline, and hygrine

저자: Lee, Jaedeok; Lee, Jae Eun; Ha, Hyun-Joon; Son, Se In; Lee, Won Koo

DOI: 10.1016/j.tetlet.2014.12.133

발행일: 2015-02-04

유형: Article

저널명: Tetrahedron Letters

권: 56

호: 6

페이지: 856 ~ 858