Application of ZKML for Unpredictive Epidemic Response

초록

We build and evaluate a concrete Zero-Knowledge Machine Learning (ZKML)-based pipeline for epidemic diagnosis and show that it can enforce computational integrity without exposing raw medical data in a Web3 setting. In response to security challenges posed by centralized data handling in medical AI applications, particularly during public health crises such as COVID-19, ZKML offers a privacy-preserving alternative by combining machine learning and Zero-Knowledge Proofs (ZKP). We experimentally applied ZKML to a CNN (Convolutional Neural Networks)-based COVID-19 diagnostic model, achieving 87% accuracy and 0.35 loss. All proof generation and verification processes were executed entirely off-chain, with the verified outputs represented as committed public_vals recorded on-chain via smart contracts. To ensure authenticity, the system enforces dual ECDSA signature verification from both the model provider and the data provider. This mechanism prevents unauthorized submissions and confirms the validity of the result before it is stored on-chain. The system was tested under both normal and adversarial conditions, demonstrating robust and reliable operation. By enabling decentralized trust and self-sovereign control over data, this architecture aligns well with Web3 principles. The results indicate that ZKML can support the development of privacy-preserving and verifiable AI systems.

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