Stereoselective synthesis of protected threo-β-hydroxy-L-glutamic acid using a chiral aziridine

Park, CS; Choi, HG; Lee, H; Lee, WK; Ha, HJ

doi:10.1016/S0957-4166(00)00311-6

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Stereoselective synthesis of protected threo-β-hydroxy-L-glutamic acid using a chiral aziridine

Park, CS;
Choi, HG;
Lee, H;
Lee, WK;
Ha, HJ

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40

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SCOPUS

44

초록

Threo-beta-hydroxy-L-glutamic acid derivatives with different carboxylic acid protecting groups were stereoselectively prepared from a chiral aziridine-2-carboxylate using an aldol reaction, stereoselective ketone reduction, and aziridine ring transformation. (C) 2000 Published by Elsevier Science Ltd.

키워드

GAMMA-CARBOXYGLUTAMIC ACID; ASYMMETRIC-SYNTHESIS; AMINO-ACIDS; EFFICIENT SYNTHESIS; MICHAEL-ADDITION; 4-METHYLENE-L-GLUTAMIC ACID; THERMODYNAMIC PREFERENCE; NEUROEXCITATORY ACTIVITY; DERIVATIVES THEREOF; ORGANIC-SYNTHESIS

제목: Stereoselective synthesis of protected threo-β-hydroxy-L-glutamic acid using a chiral aziridine

저자: Park, CS; Choi, HG; Lee, H; Lee, WK; Ha, HJ

DOI: 10.1016/S0957-4166(00)00311-6

발행일: 2000-08-25

유형: Article

저널명: Tetrahedron Asymmetry

권: 11

호: 16

페이지: 3283 ~ 3292