Synthesis of 1,2,5-and 1,2,3,5-substituted pyrroles from substituted aziridines via Ag(I)-catalyzed intramolecular cyclization

  • Kim, Jun Hee
  • Lee, Sang Bin
  • Lee, Won Koo
  • Yoon, Doo-Ha
  • Ha, Hyun-Joon
Citations

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24
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25

초록

An efficient synthesis of 1,2,5- and 1,2,3,5-substituted pyrroles has been achieved from the sequential reactions including a ring-opening of 1-(aziridin-2-yl)propargylic alcohols by various nucleophiles under mild condition followed by an intramolecular cyclization using Ag(I) catalyst. (C) 2011 Published by Elsevier Ltd.

키워드

AziridineSubstituted pyrroleIntramolecular cyclizationSilver(I) catalyzed reactionRing openingGOLD-CATALYZED CYCLIZATIONPOLYSUBSTITUTED PYRROLESEFFICIENT SYNTHESISREARRANGEMENTDERIVATIVESALKALOIDSCHEMISTRYGROWTH
제목
Synthesis of 1,2,5-and 1,2,3,5-substituted pyrroles from substituted aziridines via Ag(I)-catalyzed intramolecular cyclization
저자
Kim, Jun HeeLee, Sang BinLee, Won KooYoon, Doo-HaHa, Hyun-Joon
DOI
10.1016/j.tet.2011.02.072
발행일
2011-05-13
유형
Article
저널명
Tetrahedron
67
19
페이지
3553 ~ 3558