Macrocyclic lactam synthesis via a ring expansion reaction: Construction of the cripowellin skeleton

Moon, B; Han, S; Yoon, Y; Kwon, H

doi:10.1021/ol047520+

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Macrocyclic lactam synthesis via a ring expansion reaction: Construction of the cripowellin skeleton

Moon, B;
Han, S;
Yoon, Y;
Kwon, H

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WEB OF SCIENCE

20

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SCOPUS

23

초록

The cripowellin ring skeleton, a macrocyclic [2.3.5]-bicyclic ketolactam, was smoothly generated via construction of a spiro(benzazepin-cyclohexane-1, 3-dione) employing oxidative cyclization as a key step and a subsequent ring expansion reaction.

키워드

HYPERVALENT IODINE(III) REAGENT; PHENOLIC COUPLING REACTION; AMARYLLIDACEAE ALKALOIDS; CONVENIENT SYNTHESIS; DERIVATIVES; CYCLIZATION; ANNULATION

제목: Macrocyclic lactam synthesis via a ring expansion reaction: Construction of the cripowellin skeleton

저자: Moon, B; Han, S; Yoon, Y; Kwon, H

DOI: 10.1021/ol047520+

발행일: 2005-03-17

유형: Article

저널명: Organic Letters

권: 7

호: 6

페이지: 1031 ~ 1034