Turn-on and Turn-off Fluorescent Probes for Carbon Monoxide Detection and Blood Carboxyhemoglobin Determination

Shi, Genggongwo; Yoon, Taeseung; Cha, Seoncheol; Kim, Seulgi; Yousuf, Muhammad; Ahmed, Nisar; Kim, Doseok; Kang, Hyun-Wook; Kim, Kwang S.

doi:10.1021/acssensors.8b00083

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Turn-on and Turn-off Fluorescent Probes for Carbon Monoxide Detection and Blood Carboxyhemoglobin Determination

Shi, Genggongwo;
Yoon, Taeseung;
Cha, Seoncheol;
Kim, Seulgi;
Yousuf, Muhammad;
... Kim, Doseok;
외 3명

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초록

Water-soluble, carbazole-based two-photon excitable fluorescent probes MPVC-I ("turn-on") and MPVC-II ("turn-off") are rationally designed and synthesized for the selective monitoring of carbon monoxide (CO). Both probes can effectively measure carboxyhemoglobin (HbCO) in the blood of the animals exposed to a CO dose as low as 100 ppm for 10 min. The palladium catalyzed azidocarbonylation reaction was optimized to improve the sensing efficiency.

키워드

fluorescent probe; carbon monoxide; blood carboxyhemoglobin; gas sensing; azidocarbonylation; CATALYZED AROMATIC AZIDOCARBONYLATION; BINUCLEAR RHODIUM COMPLEXES; LIVING CELLS; SELECTIVE DETECTION; CO; AIR; RUTHENIUM(II); CARBONYLATION; COORDINATION

제목: Turn-on and Turn-off Fluorescent Probes for Carbon Monoxide Detection and Blood Carboxyhemoglobin Determination

저자: Shi, Genggongwo; Yoon, Taeseung; Cha, Seoncheol; Kim, Seulgi; Yousuf, Muhammad; Ahmed, Nisar; Kim, Doseok; Kang, Hyun-Wook; Kim, Kwang S.

DOI: 10.1021/acssensors.8b00083

발행일: 2018-06

유형: Article

저널명: ACS Sensors

권: 3

호: 6

페이지: 1102 ~ 1108